KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK5
All Species:
17.88
Human Site:
Y477
Identified Species:
35.76
UniProt:
Q6P3R8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P3R8
NP_954983.1
708
81445
Y477
L
E
E
I
R
Q
Q
Y
H
N
D
M
K
E
I
Chimpanzee
Pan troglodytes
XP_001152651
708
81377
Y477
L
E
E
I
R
Q
Q
Y
H
N
D
M
K
E
I
Rhesus Macaque
Macaca mulatta
XP_001103475
708
81434
Y477
L
E
E
I
R
Q
Q
Y
H
N
D
M
K
E
I
Dog
Lupus familis
XP_856025
1241
141182
K631
H
L
V
A
K
G
V
K
N
S
D
M
S
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSC3
627
71772
E407
E
D
T
V
Q
E
N
E
A
V
D
K
L
N
A
Rat
Rattus norvegicus
XP_001073521
655
74739
E435
K
C
R
G
E
R
E
E
D
Y
T
D
R
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
Y480
L
E
E
I
R
Q
Q
Y
H
S
D
V
K
E
I
Chicken
Gallus gallus
XP_417075
816
94076
Y457
L
Q
K
I
R
E
E
Y
H
S
N
M
R
E
F
Frog
Xenopus laevis
Q7ZZC8
944
104521
G627
L
G
I
N
L
L
G
G
P
L
G
G
K
Q
V
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
A459
L
V
Q
V
S
C
G
A
S
H
V
L
A
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LT35
416
47232
A196
G
C
C
M
F
E
V
A
A
H
Q
P
A
F
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
D531
T
E
M
I
D
S
G
D
E
S
E
A
E
A
L
Conservation
Percent
Protein Identity:
100
99.2
96.1
27.5
N.A.
39.6
37.9
N.A.
47.7
36.4
22.3
24.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.4
40.5
N.A.
52.8
51.9
N.A.
61
51.9
39.7
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
6.6
0
N.A.
86.6
46.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
20
N.A.
100
93.3
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
N.A.
23
Protein Similarity:
N.A.
N.A.
N.A.
40.9
N.A.
41.7
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
17
17
0
0
9
17
17
9
% A
% Cys:
0
17
9
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
0
0
9
9
0
50
9
0
0
0
% D
% Glu:
9
42
34
0
9
25
17
17
9
0
9
0
9
42
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
17
% F
% Gly:
9
9
0
9
0
9
25
9
0
0
9
9
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
42
17
0
0
0
0
0
% H
% Ile:
0
0
9
50
0
0
0
0
0
0
0
0
0
0
34
% I
% Lys:
9
0
9
0
9
0
0
9
0
0
0
9
42
0
9
% K
% Leu:
59
9
0
0
9
9
0
0
0
9
0
9
9
0
9
% L
% Met:
0
0
9
9
0
0
0
0
0
0
0
42
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
9
25
9
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
9
0
9
9
% P
% Gln:
0
9
9
0
9
34
34
0
0
0
9
0
0
9
0
% Q
% Arg:
0
0
9
0
42
9
0
0
0
0
0
0
17
0
0
% R
% Ser:
0
0
0
0
9
9
0
0
9
34
0
0
9
0
0
% S
% Thr:
9
0
9
0
0
0
0
0
0
0
9
0
0
0
9
% T
% Val:
0
9
9
17
0
0
17
0
0
9
9
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _